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Low-Dose Naltrexone

Compounded Low Dose Naltrexone (LDN) has gained attention in recent years for its potential benefits in various medical conditions. 


Naltrexone is traditionally used in higher doses to treat opioid addiction and alcohol dependence. However, in lower doses, typically ranging from 1.5 to 4.5 milligrams (mg) per day, it is believed to exert different effects on the body.

How Does LDN Work?

The exact mechanism of how LDN works is not fully understood, but it is thought to modulate the immune system and influence the release of certain neurotransmitters in the brain. One proposed theory is that LDN may help regulate the body's inflammatory response and promote the production of endorphins, which are natural pain-relieving chemicals.


LDN has been explored as a potential treatment for various conditions, including

  1. Autoimmune Diseases: Some studies suggest that LDN may help alleviate symptoms associated with autoimmune conditions such as multiple sclerosis, rheumatoid arthritis, and Crohn's disease.

  2. Chronic Pain: LDN has been investigated for its potential to reduce chronic pain, including neuropathic pain and fibromyalgia.

  3. Mental Health: There is some evidence to suggest that LDN may have antidepressant and mood-stabilizing effects, although more research is needed in this area.

  4. Cancer: While research is still preliminary, some studies have suggested that LDN may have anti-cancer properties and could enhance the effectiveness of certain cancer treatments.


Before starting LDN, it's essential to consult with a healthcare professional, as LDN may not be suitable for everyone. Some factors to consider include:

  • Possible Side Effects: Although LDN is generally well-tolerated, some individuals may experience side effects such as insomnia, vivid dreams, or headaches.

  • Drug Interactions: LDN may interact with certain medications, so it's crucial to inform your healthcare provider about all medications you are taking.

  • Safety: LDN should not be used by individuals with acute hepatitis or liver failure, as it may exacerbate these conditions.

Compounding You Can Trust

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